Friday, December 16, 2011

Quyen Nguyen: Color-Coded Surgery



By now you are probably well aware I am a big fan of watching videos on TED.com.

Again I would like to share with you another new 'invention' in medicine from this hub of great ideas.

Just a quick note on who Dr. Quyen Nguyen is from her bio on TED.
"Dr. Quyen Nguyen's research (working with Roger Tsien, Nobel Laureate in Chemistry) is focused on the development of fluorescently labeled probes for molecular navigation during surgery. Their first collaborative effort yieled a "smart" probe that makes tumors margins fluoresce, or "glow" and thus easier for surgeons to see and remove accurately during surgery. Their most recent joint effort resulted in another type of probe that can make nerves glow during surgery, thus helping surgeons repair injrued nerves and avoid inadvertent injury."
Now I won't bore you with the details. I highly suggest you watch the video and hear about it from her.


One other comment I would like to add is that I am salivating at the prospect this type of fluorescent marker can be used both successfully in surgeries and also in education. For years, I have been learning from color-coded textbook images and they do not pay proper respect to the complexity of anatomical and histological structures. In one of my first clinical anatomy classes, I was shocked at the lack of fine detail in the vessels, nerves, and other histological structures. Now wouldn't be cool if you could walk into a clinical class, turn off the light and see the body glow?

The advances in science and medicine has come a long way in the past 100 years and as we move further and further forward with technology, there should be a  general excitement about what we can achieve. I just hope I can still be around as long as possible to see even great advancements from the frontiers of science.

Sunday, December 11, 2011

Maybe It's Time to Quit Smoking: Part One

So as the new year rolls in, I am sure everyone is beginning to think about their resolutions. I am not a NY resolutions type of guy, but this year I have found reason to make one.

A new study published in the Proceedings of the National Academy of Science by Sleiman and Gundel et al. (2010) was undertaken to determine the effects of 'Third-Hand Smoke' (THS) and what chemicals are formed in this process (the paper was extremely littered with technical chemistry and I had to read it over and over again to make sure I got the understanding right). THS is a relatively new term coined to specify the type of lingering residue from tobacco smoke. More on this to come below. Their study also mentioned another by Matt, Quintana, and Hovell et al. (2004), who looked at contamination of indoor surfaces from environmental tobacco smoke (ETS or more commonly known as second-hand smoke) and it's effects on infants.

These two studies particularly frightened me because I can relate to them on a personal level. I have been a smoker for many years now while at the same time doing so indoors (in the confines of my room with the door closed) and have an infant (my young sister) among the household. Many friends have cautioned me to quit and while I have tried on numerous occasions, I have failed with the same amount of frequency. But these studies... they've struck a nerve.

The study by Matt, Quintana, & Hovell et al (2004) looked closely at 'second-hand smoke' and how it reacted to certain chemicals in the air to become respirable suspended particles that are difficult to filter by the protective mechanisms of the nose and throat. ETS is found to deposit on surfaces such as house dust, carpets, walls, furniture and other household objects. From there, they can be ingested by just about anyone. The main concern of the study however, was to study how it affects infants in households with indoor smokers, outdoor smokers, and a control of non-smokers.

The researchers found households had nicotine in the air of the living room (both in dust and from surfaces) and bedroom for both the indoor and outdoor smoking group. The biggest concern of the researchers was that infants had a higher respiratory rate, lower body weight, and spent more time indoors than adults. They explained this increased their likelihood and effects of exposure to ETS.

The second study looked more in-depth at the chemistry and what happens to nicotine once it had deposited on indoor surfaces (Sleiman & Gundel et al., 2010). They looked specifically at how nicotine reacted with ambient nitrous acid (HONO) to form carcinogenic tobacco-specific nitrosamines (TSNAs). (At this point you probably want to stop reading because of all these acronyms but every time I use one, it is to emphasize something terrible).

To save your sanity because I really want to drive home a certain message, I won't detail everything. The basic results of the study found that TSNAs (bad stuff) was found in significant amounts on the interior surface of a truck driven by a heavy smoker. The ETS from sorbed surfaces when exposed to HONO formed extremely carcinogenic TSNAs that were still evident after two-three hours. Exposure of this has many routes including ingestion and inhalation of contaminated dust and skin contact with contaminated surfaces. This again is more dangerous to infants than to adults.

Now that I've got the minor details out of the way. If you've managed to read up to now and considered my personal situation you can see why these studies alarmed me. While I consider myself to be fairly knowledgeable about health, I honestly did not believe my eyes when I read these articles. To some it might seem like common sense (a friend told me this recently) but it is difficult to know exactly how significant common sense is sometimes. So my warning for those who do smoke and don't wish to give it up, be considerate of where you smoke and how it might affect younger siblings and others.

In part 2 of this, I will try to look more closely at the psychological effects of quitting smoking. Hopefully I can find a few effective ways to help myself and more importantly others who wish to quit.

P.S. I found an interesting poem in the blogosphere about smoking. I have no idea what is says though because it's written in Spanish. While I find this raunchy sketch and the Spanish language extremely sexy, I particularly hate the image of a female smoking. (If you're Spanish, please feel free to translate the poem for me with comments below because Google seems to have failed me for once).



Reference:

Matt, G.E., Quintana, P.E.J., and Hovell, M.F. et al. (2004). Households contaminated by environmental tobacco smoke: sources of infant exposures. Tobacco Control, 13, 29-73.

Sleiman, M., Gundel, L.A., and Pankow, J.F. et al. (2010). Formation of carcinogens indoors by surface-mediated reactions of nicotine with nitrous acid, leading to potential thirdhand smoke hazards. PNAS, 107, 6576-6581. 

Saturday, December 10, 2011

Yoav Medan: Ultrasound surgery - healing without cuts


As I watched this video I was reminded of a quote by Thomas Edison:

"The doctors of the future will give no medicine, but will interest his patients in the care of the human body, in diet, and in the cause and prevention of disease."

I first heard the quote when I was a first-year student at university studying Chiropractic. My first ever job was also in a chiropractic and physiotherapy healthcare clinic (who later became more than just my employers but the best of friends) where the use of ultrasound was first introduced to me.

This video reminded me of all those wonderful years. I have been able to see first-hand what ultrasound technology can do in it's current limited use and application. To have been able to hear Yoav Medan talk about the advancement of this technology and the possibility of it treating so many different but critical conditions is another great victory for science and medicine.

I personally don't understand a lot about how it all works, hence why no explanation in words. If you watch the video, you can see for yourself.

And to finish, I want to leave you with another of Edison's quotes that sums up the potential for advancement in medicine if we can just embrace research and ideas:

"From his neck down a man is worth a couple of dollars a day, from his neck up he is worth anything that his brain can produce." 

Wednesday, December 7, 2011

Food on your Mind?

I haven't had much chance lately to write a proper new post due to some time constraints this week. I did however, come across this little beauty of a creation in the blogosphere and thought I would to reshare it with everyone. I initially came across it from Mind Hacks but the original can be found here by Sara Asnaghi. Clever little idea isn't it?


Anyone have food on their mind after seeing this?

I will be posting some new stuff soon so stay posted. Enjoy the rest of the week everyone.

Thursday, December 1, 2011

Decision-Making in the Blink of an Eye

As the title of this post suggests, I will be explaining your ability to make decisions.

Now this area of psychology is perhaps one of the most studied, beginning in 1848 with a case-study of a patient named Phineas Gage. This however, is not the reason I am so interested in this topic today.


The book Blink: The Power of Thinking without Thinking was one of the first ever popular psychology books I have read in my life (which is why I am reading it again for the third time). It is also one of many prominent reasons I love human nature. To quote an excerpt from this book:


Thin-slicing is not an exotic gift. It is a central part of what it means to be human. We thin-slice whenever we meet a new person or have to make sense of something quickly or encounter a novel situation. We thin-slice because we have to, and we come to rely on that ability because there are lots of hidden fists out there, lots of situations where careful attention to the details of a very thin slice, even for no more than a second or two, can tell us an awful lot. 

What Malcolm Gladwell writes about here is something I referred to in one of my earlier posts, but today I want to dig deeper into this idea called 'thin-slicing' (which by the way is an awesome name for a psychological concept). Thin-slicing is the ability of humans to make decisions in the blink of an eye without being consciously aware of how and why they have made the decision. In most cases, if the slices are coupled with experience, it can be a powerful and accurate tool. The trade-off however (there always is a disclaimer with everything isn't there), the accuracy of these decisions are more often than not wrong for complex choices. 

Another issue of thin-slicing raised by Malcolm Gladwell is the concept of being unawares of making these decisions. In situations, your ability to make decisions is incredibly fast and frugal with preciseness while your behavior in response to this decision acts accordingly yet you continue to lack awareness. One such situation was an experimental study done by Antonio Damasio et al. (1997). The authors describe the Iowa Gambling experimental procedure as:


In a gambling task that simulates real-life decision-making in the way it factors uncertainty, rewards, and penalties, the players are given four decks of cards, a loan of $2000 facsimile US bills, and asked to play so that they can lose the least amount of money and win the most. Turning each card carries an immediate reward ($100 in decks A and B and $50 in decks C and D). Unpredictably, however, the turning of some cards also carries a penalty (which is large in decks A and B and small in decks C and D). Playing mostly from the disadvantageous decks (A and B) leads to an overall loss. Playing from the advantageous decks (C and D) leads to an overall gain. The players have no way of predicting when a penalty will arise in a given deck, no way to calculate with precision the net gain or loss from each deck, and no knowledge of how many cards they must turn to end the game (the game is stopped after 100 card selections). After encountering a few losses, normal participants begin to generate skin conductance responses (SCRs i.e. sweating in the palms) before selecting a card from the bad decks and also begin to avoid the decks with large losses. Patients with bilateral damage to the ventromedial prefrontal cortices do neither. 


What the researchers found is that in normal participants, most were able to discern the "advantageous strategy" at roughly 10 cards but were considerably unaware of this until about 50 cards where they would begin to have a 'hunch' about it. It took till 80 cards before participants were able to express knowledge about the strategy (Damasio et al., 1997). This study suggests your brain has the capacity to make blink-decisions by thin-slicing and refuses to tell you about it except through galvanic skin responses. However, even at the unconscious level, behavioral changes for beneficial strategies are likely to occur thanks in large part to your brain being able to make these decisions quickly. Like in many behavioral instances, for your daily lives to run smoothly, your brain has to have the capabilities to do immense calculations for rapid-fire decisions while your awareness is catching up. 


Other research, and particularly anatomical studies of Phineas Gage, have implicated the ventromedial prefrontal cortex (if you don't know where that is just give yourself a face-palm slap above the meeting areas of the two eyebrows). In behavior studied with Gage and other patients with prefrontal cortex lesion, they can be seen to have difficulties learning from previous mistakes which causes repeated engagement in decisions that lead to negative consequences (Sanfey et al., 2003). 


So if you've ever banged your head against a table or a wall for not making the right choices for simple questions in a quiz or multiple choice exam, you are more likely to make the same mistake again if you continue to let a hard surface damage your prefrontal cortex. And if you are the type that loves to be right, well then I guess you should learn to trust your thin-slicing abilities and pay extra notice to clues from your brain to your skin. You never know, it might get you a few more correct answers in a multiple-choice exam and that all important P. 


Talking of P's, Phineas Gage is an interesting story. View the clip below for more:






References:

Damasio, A.R., Bechara, A., Damasio, H., and Tranel, D. (1997). Deciding Advantageously Before Knowing the Advantageous Strategy. Science, 275, 1293-1295.

Gladwell, M. (2006). Blink: The Power of Thinking without Thinking (eBook). Penguin Books Ltd. URL: http://books.google.com.au/ebooks?id=FiPLHNvT_NkC&dq=malcolm+gladwell+blink&as_brr=5&ei=sxjXToTGKIHUMpmW_fEI&source=webstore_onebox&redir_esc=y

Sanfey, A.G., Hastie, R., Colvin, M.K., and Grafman, J. (2003). Phineas gauged: decision-making and the human prefrontal cortex. Neuropsychologia, 41, 1218-1229.


His name is... Slim Shady!

On Friday 2nd December, Marshall Mathers III, more commonly known as Eminem and Slim Shady, will be touring Australia for the first time in over 10 years. That length of time is close to the same amount of years I have individually been a fanatic of this strange and genius hip-hop artist. In this post, I will attempt to explain the genius that is Slim with a few concepts studied in psychology. To start with, I would like readers to watch this documentary video based on parts of his life over the past 12 years.


Eminem has been a polarized figure for most of his life. Even before coming to fame, the difficulties of living in the Detroit neighborhood without a father and a drug addictive mother has had a major effect on his personality and life to date. In a review titled Metaphorical Conceptions in Hip-Hop Music, Crossley (2005)  describes the Hip Hop culture as "predominantly African-American" and rap music "is the principle medium for the expression of the worldviews of African American youth." Despite Eminem being a European American, his successful use of the hip hop culture to elevate his status has been an enigma. However, in the same review, we can find clues to uncover this riddle.

Crossley (2005) writes that rappers use metaphors to construct views about their lives. The constructivism concept states that "the objective world is not directly accessible but rather constructed on the basis of the constraining influences of human knowledge and languages where metaphors aids in creating reality." Within this concept, Eminem's success is largely based on his ability to incorporate wordplay and bending of words to build metaphors that depict the harsh realities of his life. As shown in the 60 minutes documentary, his genius can be found in the way he refuses to accept the constraints in use of words such as 'orange'. The quick-fire example he provides is just one of many underlying reasons that separates him from other hip hop artists. His ability to remain within a largely African American scene is grounded in his talent for using constructivism in a number of creative ways and doing so better than other artists.

In another view, Slim has been polarized and successful at the same time because he is consistent with much of the perspectives expressed by hip hop artists. Crossley (2005) states that "a part of hip hop's immoral philosophy finds its origin in the fact that the civil rights movement did not fulfill its promise on Black America." He goes on to say that the rap community realizes the inconsistency of "the Black urban neighborhoods as mythically emblematic of the distance American society has not covered in its effort to end segregation" Based on this, the metaphors portrayed in rap music can be seen to exemplify how African Americans have become disenfranchised with US power structures. Here, Eminem has turned the conceptual view of hip hop music on its head because he represents the non-African American group that struggles with civil institutions and systems. In the songs The Way I Am and White America, Eminem expresses this representation with simplistic and exquisite accuracy. This has allowed him to become the voice of those 'white' Americans who represent the difficult and problematic white neighborhoods.

To further discuss why I believe Eminem has been so successful, I now draw your attention to a study that looked closely at creativity in relation to intrinsic motivation and personality traits - openness to experience, self-efficacy, and perseverance (Prabhu, Sutton, & Sauser, 2008). In this study and many others before it, the authors found that intrinsic motivation has a positive relationship in mediating creativity (Hennessey & Amabile, 2010). Furthermore, they also found that openness to experience and self-efficacy (self confidence) were closely related to creativity and helped enhance its expression when coupled with intrinsic motivation.

Intrinsic motivation can be defined as an individual's intrinsic task interest which the authors propose leads to voluntary investigation of new alternatives and ideas (Prabhu, Sutton, & Sauser, 2008). For Eminem, this notion goes a long way to explaining his ability to be creative. As he explains it, he was motivated internally to succeed and become 'respected' in the hip hop scene. This motivation coupled with his belief in himself that "no matter how bad (he) was at school, no matter how low (his) grades were sometimes, (he) was always good at English." The self-efficacy and confidence he displays as well as his intrinsic desire to be good at his craft are strong reasons for his success.

In my opinion, Eminem is one of the greatest rappers of all-time (a true GOAT as they say). There can be many different explanations drawn to explain it, I have endeavored to list just a subset of what I believe makes him so great. In saying that, you don't need to read this to see how talented he is, all you would need to do is listen to this...



References:

Crossley, S. (2005). Metaphorical Conceptions in Hip Hop. African American Review, 39(4), 501-512.

Hennessey, B.A. and Amabile, T.M. (2010). Creativity. Annual Review Psychology, 61, 569-598.

Prabhu, V., Sutton, C., and Sauser, W. (2008). Creativity and Certain Personality Traits: Understanding the Mediating Effect of Intrinsic Motivation. Creativity Research Journal, 20 (1), 53-66.

Thursday, November 24, 2011

Science is the Wonder!

So, I was roaming for my daily TED talks while taking a 'study' break and I found this...




If you didn't actually watch the video and just skipped to this hoping that I was going to explain it, well... I think you would gain more from this post by taking the time to view Robin Ince's talk. Believe me, it's well worth viewing.


As Robin explains, Science has long been held as polar to the Wonders of life like art, religion, and yes, even the love of animals (what with so many scientist doing experiments on rodents). 


Here's my view of this.


Let's just say science and wonder are not dichotomies. Why should science not be viewed as a wonder in itself? Science has given us a vast majority of knowledge and experiences that in this modern age we so meekly take for granted. Let me lend credence to my view of why science is not just an education, a (future) career, and a hobby, but a joy and passion that I hold so dearly.


In 1543, Nicolaus Copernicus put science in the spotlight and religion (or was it the Church?) on the back burner by establishing the sun, not the earth, was in the center of the universe. Since that time, we have had so many shifts in paradigms that I am not sure where to begin. 


Let's skip forward a few hundred years and look at Gregor Mendel in the 1850s. The Austrian monk and Botanist was a keen experimenter with pea plants which later led to his proposition of Mendelian Law of Inheritance. If you have forgotten your high school biology lessons, the law states that every individual receives 'alleles' separately from each parent and that separate genes for separate traits are passed on independently from the parents. This discovery of course would only be the beginning (both for him and myself when I learnt it) and Mendel later became known as the father of modern genetics.


This leads me to my next scientific wonder. Now if knowing that you received alleles and traits from your parents doesn't tickle your fancy, well that's cool. What if I explained to you the discovery of DNA being a double helix by Francis Crick, James D. Watson, Maurice Wilkins, and Rosalind Franklin (yes there was a woman involved in that discovery, contrary to popular belief) in 1953 and the Human Genome Project which started in 1990 are a result of the ideas created by Mendel. The Human Genome Project is a particularly wondrous undertaking. It was initially developed by the United States and was later supported by the United Kingdom, Germany, France, and Japan. It took 13 years, costs more than $3 billion, required major advances in computer science (yes computing is a scientific field) and genomics, but eventually gave us an estimated 20 000-25 000 sequences for our genes. Seriously, consider that computers run on binomials of 1 and 0, we humans have a large many more codes for who we are which is an extraordinary discovery. 


Genetics is one of those things that is really difficult to grasp if you are not really interested, myself included. But it is key discoveries like these that make understanding genes and genetic diseases possible. Let me ask you, how many genetic diseases do you know? Surely (don't lie now) you would have thought of one or two, or maybe, you know one or two people who have or have had a genetic disease. But it is not just genetic conditions that are important, but the foundations of these discoveries has allowed important discoveries about viruses, RNA, and proteins which has then created a domino effect for other great inventions in medicine and pharmacology. These inventions have saved countless lives, and truly the wonder is in being able to preserve precious life and ensure our species survival.


Yes I said survival of our species so you're probably guessing I am about to dive into Darwinian theology. Indeed I shall. Evolution and the theory of natural selection is one of my favourite concepts in science. Why being a psychology student requires wonder itself to manifest about where we come from to understand how we came to be. So Charles Darwin's 1858 Origin of Species by Means of Natural Selection rates as one of the greatest theories in all of science (to me anyway). 


Another of the great ideas is E=mc^2. However, am I the only one who knows the equation but have absolutely no idea what it means? If someone ever tells me what it means exactly, I would be extremely grateful and hopefully I can finally sleep easier. Physics is not one of my favourite sub-disciplines, but Isaac Newton and his Laws of Motion did give us all a pretty good ending to Dan Brown's Da Vinci Code. Ok let's try not to bag out physics too much because without it, I probably would not be able to write this post on the couch while my laptop is unplugged from the power point. Alessandro Volta and Humphrey Davies inventions of the first-ever batteries in the 1800s has allowed billions of modern humans to enjoy travelling with music (yes it was scientists, not Steve Jobs, who made the iPod possible), a mobile phone, and countless other digital devices..


Why batteries is just the tip of the iceberg. Have you ever stopped to ponder about how it's possible for you to even read my blog? Blaise Pascal in 1642 invented the mechanical calculator which, I guess you could say, was the first ever form of computerized technology. It did take over 300 years before the the actual microprocessor-powered personal computer was revolutionized by Intel (who ironically were developing the processor chip for a calculator before realizing its potential for computers). The World Wide Web was, again contrary to popular folklore, developed by people at CERN - the European Organization for Nuclear Research in Geneva. All our immense leaps of technology is made possible by sciences like computer science and physics. But even that, to me, is not the most wondrous thing about science, which leads me to my final point. 


What do you think the most powerful processor is in our known world? The Human Brain. No really, it is. It has been said to be capable of processing 100 trillion instructions every second. It is the largest of all Earth's vertebrates and the most evolutionary advanced structure in the known universe. It's characteristics have been contemplated by philosophers, scientists and everyday people for thousands of years, studied extensively and rigorously for three decades, and still we have only discovered a small part of its potential. The vast amounts of functions it can exhibit and the variety of those (particularly language) is unique to human brains. And it is with biology, anatomy, neuroscience, psychiatry, and psychology that has made these discoveries possible. 


In science, there is no one singular greatest concept, idea, paradigm, theory etc. But perhaps one of the most exciting, and remarkable, has been the plasticity potential of the human brain. Neuroplasticity is a vague term that describes the potential for the the neurons in the brain to change as a result of input. For decades we have come to believe that the brain in unchangeable. Others have argued that humans are "blank slates" that can be moulded from birth and subject to changes by the environment where the brain is a "black box" that spits out behaviors. But the discovery of neuroplasticity, genetics and evolution has turned these ideas on its head and given us hope for even greater potential in ourselves. Imagine that for the first 22 years of your life you have failed to use your brain to its fullest (sounds a bit like me). This discovery heralds hope for you. Whereas before people believed that after a certain period your brain is less receptive to new learning, now, it has been shown that even debilitating neurological conditions cannot stop the amazing brain to change itself. That is the wonder of the brain (which I will explain more in another post).


That is the wonder of science. The wonder is in understanding how beautiful, immaculate, and near-perfect we are, and how much potential we have to dream and achieve something, anything that can make an impact for generations and possibly eternity. 


For other great science discoveries you can visit the Science Channel here.


And for a much better explanation of the potential of the brain, you can view the clip below.


Singing in the Rain!

In light (actually, it's rather dark and wet outside) of Sydney's terrible weather today and the numerous negative comments I've read on Facebook, I have decided to add this lighter piece to my new blog.


The weather has long been held as a major contributing factor to human psychology on days like today. I thought I might just add a few short pieces of information from some studies that investigated this effect:

Sydney Morning Herald Report 23-11-201
















  • Performance on memory tasks peaks at 22°C and declined with warmer or cooler temperature (Allen & Fischer, 1978)
  • High mood has been associated with a number of factors such as low levels of humidity (Sanders & Brizzolara, 1982), high levels of sunlight (Parrot & Sabini, 1990) and high temperature (Cunningham, 1979)
  • High temperature is reliably associated with violent behavior (Anderson, 2001)
  • High temperature and sunny weather is associated with increased mood as time spent outside increased (Keller et al., 2004)
  • Improved working memory capacity is associated with high barometric pressure or sunny weather (Keller et al., 2004)
  • Mood is also higher if you spent time outside on a clear, sunny and warm day (Keller et al., 2004)
The moral of the story is for the next few days (since the Sydney Morning Herald article says its going to be raining till Saturday), I would advise: don't attempt to study unless you can increase your room temperature to 20°-22°C; if your spouse or friend has a low mood it might be because of the weather and not whatever you just did to annoy them; don't piss a drunk off because they are more likely to be violent; spend some time inside with artificial light.

While not all the studies I have read show a conclusive and clear effect of weather on mood, those details that I have selectively presented show that weather can be a small factor involved with cognition and mood. Then again, I was only writing this post to create a lighter mood because looking outside doesn't make me feel that way at all.

The weather does give me a chance to sing this song:



Reference:

Allen, M.A., & Fischer, G.J. (1978). Ambient temperature effects on paired associate learning. Ergonomics, 21, 95-101

Anderson, C.A. (2001). Heat and violence. Current Directions in Psychological Science, 10, 33-38.

Cunningham, M.R. (1979). Weather, mood, and helping behavior: Quasi-experiments with the sunshine samaritan. Journal of Personality and Social Psychology, 37, 1947–1956.

Parrott, W.G., & Sabini, J. (1990). Mood and memory under natural conditions: Evidence for mood incongruent recall. Journal of Personality and Social Psychology, 59, 321–336.

Sanders, J.L., & Brizzolara, M.S. (1982). Relationships between weather and mood. Journal of General Psychology, 107, 155–156.

Keller, M. C., Fredrickson, B. L., Ybarra, O., Coˆte´, S., Johnson, K., Mikels, J., et al. (2005). A warm heart and a clear head: The contingent effects of weather on mood and cognition. Psychological Science, 16, 724–731.

Wood, A. (2011, November 23). Wet until Saturday, weather bureau warns. Sydney Morning Herald.

100% Debatable!

While having my coffee this morning, I spent some time reading this article in the Association for Psychological Science Journal. The paper is titled 'False-Positive Psychology: Undisclosed Flexibility in Data Collection and Analysis Allows Presenting Anything as Significant'. Remembering that I have an exam this week for research design and statistics, I thought it was rather ingenious using this paper to write a post instead of procrastinating with something completely unrelated (if you must ask, no, I am yet to peruse my social networking accounts).

I have observed in the general population a tendency to use statistics and claim them as factual when trying to make a point. This regularly occurs when one wishes to compares things. I find this particular use of statistics to be a sadly narrowed view of anything in life. One of the more common usage of this behavior can be found in sports - particularly sports like the NBA and baseball. My friends who know I have an absolute passion for Kobe Bryant will regularly use LeBron James and Michael Jordan's 'stats' as a way to compare and judge. They seem to always converge on the same conclusion, but does this make their judgement right? In everyday life, people love using percentages, ratios, and all kinds of numbers to make their point appear supported. Educators also use averages and numerical marks to rank students. But does this mean the numbers tell the whole story?

In science, particularly a science like psychology, statistical analysis is one of the most important tools of the trade. Like any tool, it can be used correctly to produce the desired result or misused (through either lack of understanding how it should be used or intentional manipulation) to fabricate a desired result.

The complexity of statistics and its varied analytic methodologies give the tool the power needed to produce an outcome. You would probably want to assume that this is an advantage of such a tool. But as Simmons, Nelson, and Simonsohn (2011) argue in their paper, a construct they term the "researcher degrees of freedom" (which I like to interpret as a personal choice for use of certain complex statistics) can lead to false-positive conclusions to be reported. It is the premise of research in psychology to find "statistically significant" results so they can reject the null hypothesis (this is like the nagging voice in your head that tells you not to do something because it can't be done). A false-positive is the incorrect rejection (or muting the volume) of this nag.

They also go on to state "it is common (and accepted practice) for researchers to explore various analytic alternatives, to search for a combination that yields statistical significance, and to then report only what worked." Put simply, this statement can explain what most of us tend to do - we explore different percentages, ratios, and stats, search for the combination that best fits our argument and then we report them to our friends. While many methods in research have been developed to rid us of this simple but flawed occurrence, the researchers of this paper nonetheless report it to transpire regularly - even among what is supposed to be objective and highly intellectual individuals. They then go on to explain this as being the result of "ambiguity in how best to make (these) decisions" and "the researcher's desire to find a statistically significant result." The former can be interpreted simply as a layman's lack of absolute understanding for whatever it is they are arguing and the latter as a self-serving bias because humans tend to want to be right.

While this paper goes on to produce its own experiment and simulations to make their case, I will not be continuing to analyse the rest of the paper for this post. I am personally not reviewing this research paper, but I do have something to add. While most scientists aspire to find the truth about human nature, I do not believe they would willingly endanger our species with fabricated results. Much of statistics is built upon being objective, but the initial input and final interpretation of this data is subject to human intervention. As humans we can never be perfect (ironically it was psychologists who showed us this) and thus we must admit that mistakes are possible and will happen (luckily, even when psychology studies are wrong, they don't necessarily cause harmful physiological damage). To be wrong is a necessity to eventually finding the truth if we are willing to explore further. Any attempt to find the truth the first few times something is investigated is a difficult ask. As social beings, collaboration should be encouraged to undertake further research and that way, the truth cannot be subjected to just one human mistake (or in some cases, human manipulation).

Exploration is important for humans. When people make their case by promptly bringing up some supporting statistic, they are hindering the opportunity to explore. If we as a species are handcuffed by this with a narrowing of our views based on statistics, the possibilities of learning are now redundant. There are many human factors that affect an outcome in our human world. To simply boil these down to a number would be like viewing our world in the machinery of robots and computers.

For anyone that is rather bored and wishes to explore numbers visually, here is a link to Gap Minder (yet another brilliant Google collaboration).

And for anyone who has 6 minutes to spare, this is a really funny use of statistics for TED Talks.


Reference:

Simmons, J. P., Nelson, L. D., & Simonsohn, U. (2011). False-Positive Psychology: Undisclosed Flexibility in Data Collection and Analysis Allows Presenting Anything as Significant. Psychological Science, 22, 1359-1366.



Tuesday, November 22, 2011

A Paradoxical Sight

Almost everyone has heard of the saying "seeing is believing." My question to you is, do you believe you are aware of everything you see? Well, up until a few months ago (even though I study science and understand there are some strange complex things that occur in our brain we are not aware of), I would claim this is very much true.

What changed my belief of this was a lecture on the visual pathway and processing structures in the brain. To summarize what I have learnt without going into too much detail. Visual perception occurs when a light hits the back of your retina and stimulates the rods and cones to send a nerve impulse (an electrical stimuli similar to your power cables) to your brain. A specific area in the back of the brain called the primary visual area (V1) is one of the important structures that allows you to perceive what you see. Now the important thing is, V1 has been described by neuroscientists as necessary but not sufficient for 'conscious' awareness of visual stimuli. The other side of the story are specific extrastriate areas required to communicate with the V1 area for awareness of visual phenomenons like motion, color, and shape.

So what does all of this have to do with awareness? The thing I find remarkable about neuroscience is that they can only study certain aspects of brain function when and if there is someone with a lesion to specific structures. This means they're in the business of proving the saying "you don't know what you've got until it's gone."

Now one of the more interesting things that has been studied in the past 10 years has been blindsight. In 1996, Weiskrantz et al., did experiments on a patient with a lesion to the primary visual cortex (his name was D.B.) who, when prompted to do so, was able to identify visual figures and follow targets with his fingers while reporting to do so in the absence of visual consciousness. Remember I said before that V1 is necessary for conscious awareness of what you see? How is it possible then that someone with damage to V1 can be aware of something they cannot possibly see? The experiments found that D.B. was able to discriminate between two possible stimuli such as an X vs. an O or horizontal lines vs. vertical lines with an above chance performance. In later studies, it was described by D.B. as having "a strong feeling of something being there" despite not being aware of it.

So it seems (from a visual perspective in any case) that we are not always 'aware' of everything we see. In the video below, Dr. V. S. Ramachandran attempts to explain this requirement as a necessary feature of everyday life. It is indeed staggering if you stop for a second to consider how many physical phenomenons your brain has to perceive in a short time for you to do something as simple as crossing the road at a traffic light (e.g. the motion of moving cars, the position of your body relative to the car, the colour of the light etc). It is indeed necessary for us to be unaware of a large amount of processing for you to be able to function.


If you still don't believe you are not aware of everything. Well, try this test:



Reference:

Overgaard, M. (2011). Visual experience and blindsight: a methodological review. Experimental Brain Research 209: 473-479.

Hello!

So... what is this blog all about you're wondering?

Inspired by my love for human nature and the complexly intricate human mind, I have decided to share with you my journey as I learn about its workings. I am psychology student who loves explaining to others how they behave and why. And that very question, 'why', is the foundation of this blog.

Am I here to blog about why you exist or the meaning of life?

Well, no.

What I aspire to write about are those idiosyncrasies you never thought had any meaning. Those little peculiar, eccentric, quirky traits that make each and every one of us individuals and collectively humans. Along the way, I hope to use just some of those research papers psychologists and neuroscientists have written to show to you why we do certain things.

If you are wondering if my blog will be just another one of those psychology blogs written by professionals and PhD academics, then you should probably stop right about now. To begin with, I just want to make it clear I do not claim to be a psychologist or a distinguished member of their society. But as it is my hope to one day join them, I thought it would be good practice to polish my writing skills. So while I will spend some time analysing journal articles and research papers, I purposely started a blog because I know for certain I won't be given a numerical or academic mark for my entries. To me, its amazing when you can learn without worrying about an assessment. And this is where I hope to take my blog: a destination of learning and freely speaking my mind without the burden grades and scores.

Now while I wish to write freely, I understand that I am not unhindered by criticism and evaluation. In fact, I hope that readers of my blog will find the time to give me their opinion of the topics I write about. This blog is about practice and training my writing skills, and if I am not open to critics then I guess I will never learn. So if you like what you read, and don't like the way you have read it (or vice versa), then please tell me so. I will endeavour to read all your comments and regularly update my writing style to make sure the quality is in line with other bloggers and writers.

Finally, I would like to say I live my life reading and finding meaning in quotes. So here are a few I would love to share in my first entry.

Aristotle once said "all men by nature desire knowledge" (and I guess in this modern age, we must also politically remember that women deserve the same acknowledgement). For this reason, I love learning and I hope you do too. Learning about concepts and ideas is one of the many wondrous abilities of the human mind. Learning about ourselves and who we are is perhaps one of the greatest of our abilities.

A few hundred years after our Greek philosopher, Albert Einstein said "If you can't explain it simply, you don't understand it well enough." I find this quote to apply to my blog. As I have already explained, I do not consider myself an accomplished or expert writer. I simply wish to compose entries about the psychology of humans in as simple terms as I possibly can. As the years progress and I go further into my education, perhaps with the help of my academic institution and this blog, I will become a proficient writer.

Good reading everyone and I hope you've enjoyed it enough to come back again soon. I will have my next post as soon as possible.


A. Che